Anti-GSTA2 Antibody

Rs. 45,619.00
SKU stj29991

General Information

Product name Anti-GSTA2 Antibody
Short Description Rabbit polyclonal to GSTA2
Description Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-GSTA2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA2 (NP_000837.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 25.7 kDa
Database Links
Alternative Names GSTA2Glutathione S-transferase A2 GSTA2 antibodyGST2
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
Cellular Localization Cytoplasm
Tissue Specificity Liver
Swiss-Prot Key

 

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