Anti-GSTT1 Antibody

Rs. 45,619.00
SKU stj29845

General Information

Product name Anti-GSTT1 Antibody
Short Description Rabbit polyclonal to GSTT1
Description The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-GSTT1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GSTT1 (NP_000844.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 27.3 kDa
Database Links
Alternative Names GSTT1Glutathione S-transferase theta-1 GSTT1
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles, Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide, Displays glutathione peroxidase activity with cumene hydroperoxide.
Cellular Localization Cytoplasm
Tissue Specificity Found in erythrocyte, expressed at low levels in liver, in lung, expressed at low levels in clara cells and ciliated cells at the alveolar/bronchiolar junction, absent from epithelial cells of larger bronchioles.
Swiss-Prot Key

 

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