Anti-GYPC Antibody

Rs. 45,619.00
SKU stj23898

General Information

Product name Anti-GYPC Antibody
Short Description Rabbit polyclonal to GYPC
Description Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-GYPC Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human GYPC (NP_002092.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 13.8 kDa
Database Links
Alternative Names GYPCGlycophorin-C antibodyGlycoconnectin antibodyGlycophorin-D antibodyGPD antibodyGlycoprotein beta antibodyPAS-2' antibodySialoglycoprotein D antibodyCD antigen CD236GYPC antibodyGLPC antibodyGPC
Function This protein is a minor sialoglycoprotein in human erythrocyte membranes, The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain, Glycophorin-C plays an important role in regulating the stability of red cells
Cellular Localization Cell membrane
Tissue Specificity Glycophorin-c is expressed in erythrocytes, glycophorin-d and isogpc are ubiquitously expressed.
Swiss-Prot Key

 

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