Anti-GZMA Antibody

Rs. 57,098.00
SKU stj71899

General Information

Product name Anti-GZMA Antibody
Short Description Goat polyclonal to GZMA
Description
Applications ELISA
Dilution range
Protein Name Anti-GZMA Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 29 kDa
Database Links
Alternative Names GZMAGranzyme A GZMA antibodyCTLA3 antibodyHFSP
Function Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse, It cleaves after Lys or Arg, Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity, Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA,
Cellular Localization Isoform alpha: Secreted, Cytoplasmic granule
Tissue Specificity
Swiss-Prot Key

 

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