Anti-HAMP Antibody

Rs. 68,577.00
SKU stj71808

General Information

Product name Anti-HAMP Antibody
Short Description Goat polyclonal to HAMP
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-HAMP Antibody
Immunogen N Terminus (near)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 9.4 kDa
Database Links
Alternative Names HAMPHepcidin antibodyLiver-expressed antimicrobial peptide 1 antibodyLEAP-1 antibodyPutative liver tumor regressor antibodyPLTRHAMP antibodyHEPC antibodyLEAP1 antibodyUNQ487/PRO1003
Function Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues, Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma, Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes ,
Cellular Localization Secreted
Tissue Specificity Highest expression in liver and to a lesser extent in heart and brain, low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland, secreted into the urine,
Swiss-Prot Key

 

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