Anti-HAND1 antibody

Rs. 50,211.00
SKU stj92865

General Information

Product name Anti-HAND1 antibody
Short Description
Description Rabbit polyclonal to HAND1.
Applications IF,ELISA
Dilution range IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-HAND1 antibody
Immunogen Synthesized peptide derived from human HAND1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 23.627 kDa
Database Links
Alternative Names Heart- and neural crest derivatives-expressed protein 1 antibody
Class A basic helix-loop-helix protein 27 antibody
bHLHa27 antibody
Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 antibody
eHAND antibody
BHLHA27 antibody
EHAND antibody
Function Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) .
Cellular Localization Nucleus, nucleoplasm Nucleus, nucleolus. Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity .
Tissue Specificity Heart.
Swiss-Prot Key

 

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