Anti-HARS2 Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110095

General Information

Product name Anti-HARS2 Antibody
Short Description Rabbit polyclonal to HARS2
Description Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Probable histidine--tRNA ligasemitochondrial
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 217-506 of human HARS2 (NP_036340.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.9 kDa
Database Links
Alternative Names HARS2Probable histidine--tRNA ligase antibodymitochondrial HARS2 antibodyHARSL antibodyHARSR antibodyHO3
Function
Cellular Localization Mitochondrion matrix
Tissue Specificity A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver
Swiss-Prot Key

 

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