Anti-HBEGF Antibody

Rs. 45,619.00
SKU stj27528

General Information

Product name Anti-HBEGF Antibody
Short Description Rabbit polyclonal to HBEGF
Description
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-HBEGF Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human HBEGF (NP_001936.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 23.1 kDa
Database Links
Alternative Names HBEGFProheparin-binding EGF-like growth factor HBEGF antibodyDTR antibodyDTS antibodyHEGFL
Function Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4, Required for normal cardiac valve formation and normal heart function, Promotes smooth muscle cell proliferation, May be involved in macrophage-mediated cellular proliferation, It is mitogenic for fibroblasts, but not endothelial cells, It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF, Also acts as a diphtheria toxin receptor
Cellular Localization Heparin-binding EGF-like growth factor: Secreted, extracellular space, Single-pass type I membrane protein
Tissue Specificity
Swiss-Prot Key

 

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