Anti-hCAP-G antibody

Rs. 50,211.00
SKU stj93469

General Information

Product name Anti-hCAP-G antibody
Short Description
Description Rabbit polyclonal to hCAP-G.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:40000
Protein Name Anti-hCAP-G antibody
Immunogen Synthesized peptide derived from human hCAP-G
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 115 kDa
Database Links
Alternative Names Condensin complex subunit 3 antibody
Chromosome-associated protein G antibody
Condensin subunit CAP-G antibody
Melanoma antigen NY-MEL-3 antibody
Non-SMC condensin I complex subunit G antibody
XCAP-G homolog antibody
CAPG antibody
NYMEL3 antibody
Function Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Cellular Localization Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Tissue Specificity Highly expressed in testis.
Swiss-Prot Key

 

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