Anti-HIRA antibody

Rs. 50,211.00
SKU stj93503

General Information

Product name Anti-HIRA antibody
Short Description
Description Rabbit polyclonal to HIRA.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-HIRA antibody
Immunogen Synthesized peptide derived from human HIRA around the non-phosphorylation site of T555.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 111.835 kDa
Database Links
Alternative Names Protein HIRA antibody
TUP1-like enhancer of split protein 1 antibody
DGCR1 antibody
HIR antibody
TUPLE1 antibody
Function Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Cellular Localization Nucleus. Nucleus, PML body. Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.
Tissue Specificity Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta.
Swiss-Prot Key

 

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