General Information
| Product name | Anti-Histone H2B antibody |
|---|---|
| Short Description | |
| Description | Rabbit polyclonal to Histone H2B. |
| Applications | WB,IHC,IF,ELISA |
| Dilution range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Protein Name | Anti-Histone H2B antibody |
| Immunogen | Synthesized peptide derived from human Histone H2B around the non-acetylation site of K12 |
| Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Mouse,Monkey |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 14 kDa |
| Database Links | |
| Alternative Names | Histone H2B type F-S antibody.s antibody H2B/s antibody |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. |
| Cellular Localization | Nucleus. Chromosome. |
| Tissue Specificity | |
| Swiss-Prot Key |