Anti-HLA-DOA Antibody

Rs. 45,619.00
SKU stj29003

General Information

Product name Anti-HLA-DOA Antibody
Short Description Rabbit polyclonal to HLA-DOA
Description HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-HLA-DOA Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 26-135 of human HLA-DOA (NP_002110.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 27.6 kDa
Database Links
Alternative Names HLA-DOAHLA class II histocompatibility antigen antibodyDO alpha chain antibodyMHC DN-alpha antibodyMHC DZ alpha antibodyMHC class II antigen DOAHLA-DOA antibodyHLA-DNA antibodyHLA-DZA
Function Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells, Modifies peptide exchange activity of HLA-DM
Cellular Localization Endosome membrane
Tissue Specificity
Swiss-Prot Key

 

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