Anti-HMGB3 Antibody

Rs. 68,577.00
SKU stj71871

General Information

Product name Anti-HMGB3 Antibody
Short Description Goat polyclonal to HMGB3
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-HMGB3 Antibody
Immunogen internal region (near C Terminus)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 23 kDa
Database Links
Alternative Names HMGB3High mobility group protein B3 antibodyHigh mobility group protein 2a antibodyHMG-2a antibodyHigh mobility group protein 4 antibodyHMG-4HMGB3 antibodyHMG2A antibodyHMG4
Function Multifunctional protein with various roles in different cellular compartments, May act in a redox sensitive manner, Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity), Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity), Negatively regulates B-cell and myeloid cell differentiation, In hematopoietic stem cells may regulate the balance between self-renewal and differentiation, Involved in negative regulation of canonical Wnt signaling (By similarity),
Cellular Localization Nucleus
Tissue Specificity Expressed predominantly in placenta
Swiss-Prot Key

 

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