Anti-HNRNPH1 Antibody

Rs. 45,619.00
SKU stj27720

General Information

Product name Anti-HNRNPH1 Antibody
Short Description Rabbit polyclonal to HNRNPH1
Description This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-HNRNPH1 Antibody
Immunogen A synthetic peptide of human HNRNPH1
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 49.2 kDa
Database Links
Alternative Names HNRNPH1Heterogeneous nuclear ribonucleoprotein H antibodyhnRNP HHNRNPH1 antibodyHNRPH antibodyHNRPH1
Function This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm, Mediates pre-mRNA alternative splicing regulation, Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast, Binds to the IR RNA, Binds poly(RG).
Cellular Localization Nucleus, nucleoplasm
Tissue Specificity Expressed ubiquitously
Swiss-Prot Key

 

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