Anti-HOOK1 Antibody

Rs. 45,619.00
SKU stj26831

General Information

Product name Anti-HOOK1 Antibody
Short Description Rabbit polyclonal to HOOK1
Description This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-HOOK1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 489-728 of human HOOK1 (NP_056972.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 84.6 kDa
Database Links
Alternative Names HOOK1Protein Hook homolog 1 antibodyh-hook1 antibodyhHK1HOOK1
Function Required for spermatid differentiation, Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity), Component of the FTS/Hook/FHIP complex (FHF complex), The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
Cellular Localization Cytoplasm.
Tissue Specificity
Swiss-Prot Key

 

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