Anti-HSD17B10 Antibody

Rs. 45,619.00
SKU stj27401

General Information

Product name Anti-HSD17B10 Antibody
Short Description Rabbit polyclonal to HSD17B10
Description This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-HSD17B10 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human HSD17B10 (NP_004484.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 26.9 kDa
Database Links
Alternative Names HSD17B103-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 antibodyERAB antibodyHADH2 antibodyMRPP2 antibodySCHAD antibodySDR5C1 antibodyXH98G2
Function Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone.
Cellular Localization Mitochondrion
Tissue Specificity Ubiquitously expressed in normal tissues but is overexpressed in neurons affected in ad.
Swiss-Prot Key

 

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