Anti-Htr1a Antibody

Rs. 68,577.00
SKU stj72615

General Information

Product name Anti-Htr1a Antibody
Short Description Goat polyclonal to Htr1a (mouse)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Htr1a Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 46.2 kDa
Database Links
Alternative Names Anti-Htr1a (mouse) Antibody
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), Also functions as a receptor for various drugs and psychoactive substances, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase, Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways, Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores, Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism, Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior, Plays a role in the response to anxiogenic stimuli,
Cellular Localization Cell membrane
Tissue Specificity Most abundantly expressed in midbrain, in dorsal raphe and hippocampus, detected at lower levels in amygdala and brain cortex,
Swiss-Prot Key

 

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