Anti-HTR2C Antibody

Rs. 68,577.00
SKU stj70718

General Information

Product name Anti-HTR2C Antibody
Short Description Goat polyclonal to HTR2C
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-HTR2C Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 51.8 kDa
Database Links
Alternative Names HTR2C5-hydroxytryptamine receptor 2C antibody5-HT-2C antibody5-HT2C antibody5-HTR2C antibody5-hydroxytryptamine receptor 1C antibody5-HT-1C antibody5-HT1C antibodySerotonin receptor 2CHTR2C antibodyHTR1C
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD), Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways, Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores, Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone, Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress, Plays a role in insulin sensitivity and glucose homeostasis,
Cellular Localization Cell membrane
Tissue Specificity Detected in brain,
Swiss-Prot Key

 

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