Anti-IDH2 Antibody

Rs. 45,619.00
SKU stj29270

General Information

Product name Anti-IDH2 Antibody
Short Description Rabbit polyclonal to IDH2
Description Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Applications WB,IHC,IF,IP,ChIP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50
IP 1:50 - 1:200
ChIP 1:20 - 1:100
Protein Name Anti-IDH2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 193-452 of human IDH2 (NP_002159.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 50.9 kDa
Database Links
Alternative Names IDH2Isocitrate dehydrogenase antibodymitochondrial antibodyIDHIDH2
Function Plays a role in intermediary metabolism and energy production, It may tightly associate or interact with the pyruvate dehydrogenase complex
Cellular Localization Mitochondrion
Tissue Specificity
Swiss-Prot Key

 

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