Anti-IFT57 Antibody

Rs. 68,577.00
SKU stj71890

General Information

Product name Anti-IFT57 Antibody
Short Description Goat polyclonal to IFT57
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-IFT57 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 49.1 kDa
Database Links
Alternative Names IFT57Intraflagellar transport protein 57 homolog antibodyDermal papilla-derived protein 8 antibodyEstrogen-related receptor beta-like protein 1 antibodyHIP1-interacting protein antibodyMHS4R2IFT57 antibodyDERP8 antibodyESRRBL1 antibodyHIPPI
Function Required for the formation of cilia, Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity), Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis, Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator
Cellular Localization Cytoplasm, cytoskeleton, cilium basal body
Tissue Specificity Present in many tissues such as brain, thymus, lymph node, lung, liver, skin and kidney (at protein level),
Swiss-Prot Key

 

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