Anti-IGF2BP2 Antibody

Rs. 68,577.00
SKU stj71433

General Information

Product name Anti-IGF2BP2 Antibody
Short Description Goat polyclonal to IGF2BP2
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-IGF2BP2 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 66.1 kDa
Database Links
Alternative Names IGF2BP2Insulin-like growth factor 2 mRNA-binding protein 2 antibodyIGF2 mRNA-binding protein 2 antibodyIMP-2 antibodyHepatocellular carcinoma autoantigen p62 antibodyIGF-II mRNA-binding protein 2 antibodyVICKZ family member 2IGF2BP2 antibodyIMP2 antibodyVICKZ2
Function RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs), This transcript 'caging' into mRNPs allows mRNA transport and transient storage, It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity), Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs, Binding is isoform-specific, Binds to beta-actin/ACTB and MYC transcripts,
Cellular Localization Nucleus, Cytoplasm,
Tissue Specificity Expressed in oocytes, granulosa cells of small and growing follicles, leydig cells, spermatogonia and semen (at protein level), expressed in testicular cancer (at protein level), expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas, detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis,
Swiss-Prot Key

 

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