Anti-IHH Antibody

Rs. 45,619.00
SKU stj28709

General Information

Product name Anti-IHH Antibody
Short Description Rabbit polyclonal to IHH
Description This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IHH Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human IHH (NP_002172.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 45.3 kDa
Database Links
Alternative Names IHHIndian hedgehog protein antibodyIHH antibodyHHG-2IHH
Function Intercellular signal essential for a variety of patterning events during development, Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes, Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones, Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
Cellular Localization Indian hedgehog protein N-product: Cell membrane
Tissue Specificity Expressed in embryonic lung, and in adult kidney and liver
Swiss-Prot Key

 

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