Anti-IKZF4 Antibody

Rs. 57,098.00
SKU stj72126

General Information

Product name Anti-IKZF4 Antibody
Short Description Goat polyclonal to IKZF4
Description
Applications ELISA
Dilution range
Protein Name Anti-IKZF4 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 64.1 kDa
Database Links
Alternative Names IKZF4Zinc finger protein Eos antibodyIkaros family zinc finger protein 4IKZF4 antibodyKIAA1782 antibodyZNFN1A4
Function DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence, Transcriptional repressor, Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2, May be involved in the development of central and peripheral nervous systems, Essential for the inhibitory function of regulatory T-cells (Treg), Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity),
Cellular Localization Nucleus
Tissue Specificity Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen, expressed in the hematopoietic cell lines molt-4, nalm-6 and k-562, highly expressed in thp-1 and m-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively,
Swiss-Prot Key

 

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