Anti-IL-11Rα antibody

Rs. 50,211.00
SKU stj93675

General Information

Product name Anti-IL-11Rα antibody
Short Description
Description Rabbit polyclonal to IL-11Rα.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:20000
Protein Name Anti-IL-11Rα antibody
Immunogen Synthesized peptide derived from human IL-11Rα
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 45 kDa
Database Links
Alternative Names Interleukin-11 receptor subunit alpha antibody
IL-11 receptor subunit alpha antibody
IL-11R subunit alpha antibody
IL-11R-alpha antibody
IL-11RA antibody
Function Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Cellular Localization Membrane. Single-pass type I membrane protein.
Tissue Specificity Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.
Swiss-Prot Key

 

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