Anti-IL11 Antibody

Rs. 45,619.00
SKU stj29870

General Information

Product name Anti-IL11 Antibody
Short Description Rabbit polyclonal to IL11
Description The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-IL11 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-199 of human IL11 (NP_000632.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 21.4 kDa
Database Links
Alternative Names IL11Interleukin-11 antibodyIL-11 antibodyAdipogenesis inhibitory factor antibodyAGIF antibodyOprelvekinIL11
Function Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production , Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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