Anti-IL13RA1 Antibody

Rs. 45,619.00
SKU stj28711

General Information

Product name Anti-IL13RA1 Antibody
Short Description Rabbit polyclonal to IL13RA1
Description The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IL13RA1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-343 of human IL13RA1 (NP_001551.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.8 kDa
Database Links
Alternative Names IL13RA1Interleukin-13 receptor subunit alpha-1 antibodyIL-13 receptor subunit alpha-1 antibodyIL-13R subunit alpha-1 antibodyIL-13R-alpha-1 antibodyIL-13RA1 antibodyCancer/testis antigen 19 antibodyCT19 antibodyCD antigen CD213a1IL13RA1 antibodyIL13R antibodyIL13RA
Function Binds with low affinity to interleukin-13 (IL13), Together with IL4RA can form a functional receptor for IL13, Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity
Cellular Localization Membrane
Tissue Specificity Ubiquitous, highest levels in heart, liver, skeletal muscle and ovary
Swiss-Prot Key

 

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