Anti-IL21R Antibody

Rs. 45,619.00
SKU stj29604

General Information

Product name Anti-IL21R Antibody
Short Description Rabbit polyclonal to IL21R
Description The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IL21R Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 59.1 kDa
Database Links
Alternative Names IL21RInterleukin-21 receptor antibodyIL-21 receptor antibodyIL-21R antibodyNovel interleukin receptor antibodyCD antigen CD360IL21R antibodyNILR antibodyUNQ3121/PRO10273
Function This is a receptor for interleukin-21
Cellular Localization Membrane
Tissue Specificity Selectively expressed in lymphoid tissues, most highly expressed in thymus and spleen
Swiss-Prot Key

 

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