Anti-IL22RA2 Antibody

Rs. 45,619.00
SKU stj29225

General Information

Product name Anti-IL22RA2 Antibody
Short Description Rabbit polyclonal to IL22RA2
Description This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IL22RA2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-231 of human IL22RA2 (NP_851826.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 30.6 kDa
Database Links
Alternative Names IL22RA2Interleukin-22 receptor subunit alpha-2 antibodyIL-22 receptor subunit alpha-2 antibodyIL-22R-alpha-2 antibodyIL-22RA2 antibodyCytokine receptor class-II member 10 antibodyCytokine receptor family 2 member 10 antibodyCRF2-10 antibodyCytokine receptor family type 2 antibodysoluble 1 antibodyCRF2-S1 antibodyInterleukin-22-binding protein antibodyIL-22BP antibodyIL22BP antibodyZcytoR16IL22RA2 antibodyUNQ5793/PRO19598/PRO19822
Function Isoform 2 is a receptor for IL22, Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro), May play an important role as an IL22 antagonist in the regulation of inflammatory responses
Cellular Localization Secreted
Tissue Specificity Expressed in placenta, spleen, breast, skin and lung, also detected in intestinal tract, testis, brain, heart and thymus, no expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus, isoform 1 is expressed only in placenta, isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
Swiss-Prot Key

 

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