Anti-INTS6 Antibody

Rs. 45,619.00
SKU stj28717

General Information

Product name Anti-INTS6 Antibody
Short Description Rabbit polyclonal to INTS6
Description DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-INTS6 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human INTS6 (NP_036273.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 100.4 kDa
Database Links
Alternative Names INTS6Integrator complex subunit 6 antibodyInt6 antibodyDBI-1 antibodyProtein DDX26 antibodyProtein deleted in cancer 1 antibodyDICE1INTS6 antibodyDBI1 antibodyDDX26 antibodyDDX26A
Function Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable), Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Cellular Localization Nucleus
Tissue Specificity Widely expressed, expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Swiss-Prot Key

 

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