Anti-IPO8 Antibody

Rs. 68,577.00
SKU stj70214

General Information

Product name Anti-IPO8 Antibody
Short Description Goat polyclonal to IPO8
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-IPO8 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 119.9 kDa
Database Links
Alternative Names IPO8Importin-8 antibodyImp8 antibodyRan-binding protein 8 antibodyRanBP8IPO8 antibodyRANBP8
Function Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1, Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism, At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran, The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus, In vitro mediates the nuclear import of SRP19,
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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