Anti-IRF-4 antibody

Rs. 50,211.00
SKU stj93764

General Information

Product name Anti-IRF-4 antibody
Short Description
Description Rabbit polyclonal to IRF-4.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-IRF-4 antibody
Immunogen Synthesized peptide derived from human IRF-4
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 45 kDa
Database Links
Alternative Names Interferon regulatory factor 4 antibody
Lymphocyte-specific interferon regulatory factor antibody
LSIRF antibody
Multiple myeloma oncogene 1 antibody
NF-EM5 antibody
MUM1 antibody
Function Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes .
Cellular Localization Nucleus.
Tissue Specificity Lymphoid cells.
Swiss-Prot Key

 

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