Anti-IRF6 Antibody

Rs. 45,619.00
SKU stj28002

General Information

Product name Anti-IRF6 Antibody
Short Description Rabbit polyclonal to IRF6
Description This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IRF6 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 115-300 of human IRF6 (NP_006138.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.1 kDa
Database Links
Alternative Names IRF6Interferon regulatory factor 6 antibodyIRF-6IRF6
Function Probable DNA-binding transcriptional activator, Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity), Plays a role in regulating mammary epithelial cell proliferation (By similarity), May regulate WDR65 transcription (By similarity).
Cellular Localization Nucleus
Tissue Specificity Expressed in normal mammary epithelial cells, expression is reduced or absent in breast carcinomas.
Swiss-Prot Key

 

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