Anti-IRF8 Antibody

Rs. 45,619.00
SKU stj28362

General Information

Product name Anti-IRF8 Antibody
Short Description Rabbit polyclonal to IRF8
Description Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-IRF8 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.4 kDa
Database Links
Alternative Names IRF8Interferon regulatory factor 8 antibodyIRF-8 antibodyInterferon consensus sequence-binding protein antibodyH-ICSBP antibodyICSBPIRF8 antibodyICSBP1
Function Plays a role as a transcriptional activator or repressor.
Cellular Localization Nucleus
Tissue Specificity Predominantly expressed in lymphoid tissues.
Swiss-Prot Key

 

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