Anti-JIK antibody

Rs. 50,211.00
SKU stj93798

General Information

Product name Anti-JIK antibody
Short Description
Description Rabbit polyclonal to JIK.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:10000
Protein Name Anti-JIK antibody
Immunogen Synthesized peptide derived from human JIK
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 110 kDa
Database Links
Alternative Names Serine/threonine-protein kinase TAO3 antibody
Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody
CTCL-associated antigen HD-CL-09 antibody
Dendritic cell-derived protein kinase antibody
JNK/SAPK-inhibitory kinase antibody
Jun kinase-inhibitory kinase antibody
Kinase from chicken homolog A antibody
hKFC-A antibody
Thousand and one amino acid protein 3 antibody
DPK antibody
KDS antibody
MAP3K18 antibody
Function Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
Cellular Localization Cytoplasm Cell membrane. Also localized to the peripheral cell membrane.
Tissue Specificity Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Swiss-Prot Key

 

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