Anti-KDM2B Antibody

Rs. 68,577.00
SKU stj70403

General Information

Product name Anti-KDM2B Antibody
Short Description Goat polyclonal to KDM2B
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-KDM2B Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 152.6 kDa
Database Links
Alternative Names KDM2BLysine-specific demethylase 2B KDM2B antibodyCXXC2 antibodyFBL10 antibodyFBXL10 antibodyJHDM1B antibodyPCCX2
Function Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code, Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36', Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation, May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex,
Cellular Localization Nucleus, nucleolus
Tissue Specificity
Swiss-Prot Key

 

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