Anti-KDM5B Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110083

General Information

Product name Anti-KDM5B Antibody
Short Description Rabbit polyclonal to KDM5B
Description This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Lysine-specific demethylase 5B
Immunogen Recombinant protein of human KDM5B
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 175.7 kDa
Database Links
Alternative Names KDM5BLysine-specific demethylase 5B KDM5B antibodyJARID1B antibodyPLU1 antibodyRBBP2H1
Function Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.
Cellular Localization Nucleus
Tissue Specificity Ubiquitously expressed, with highest levels in testis, down-regulated in melanoma and glioblastoma, up-regulated in breast cancer (at protein level).
Swiss-Prot Key

 

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