Anti-KLF15 Antibody

Rs. 68,577.00
SKU stj70188

General Information

Product name Anti-KLF15 Antibody
Short Description Goat polyclonal to KLF15
Description
Applications ELISA, WB, FC
Dilution range
Protein Name Anti-KLF15 Antibody
Immunogen N Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 44 kDa
Database Links
Alternative Names KLF15Krueppel-like factor 15 antibodyKidney-enriched krueppel-like factorKLF15 antibodyKKLF
Function Transcriptional regulator that binds to the GA element of the CLCNKA promoter, Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity), Is a repressor of CTGF expression, involved in the control of cardiac fibrosis, It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity), Involved in podocyte differentiation (By similarity), Inhibits MYOCD activity, Is a negative regulator of TP53 acetylation, Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation,
Cellular Localization Nucleus
Tissue Specificity Highly expressed in liver, skeletal muscle, and kidney, expressed in cardiomyocytes, expression is highly reduced in cardiac tissue of patients with non-ischemic cardiomyopathy and aortic aneurysm, and in glomerular disease, not expressed in bone marrow or lymphoid tissues,
Swiss-Prot Key

 

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