Anti-KLK11 Antibody

Rs. 45,619.00
SKU stj28724

General Information

Product name Anti-KLK11 Antibody
Short Description Rabbit polyclonal to KLK11
Description Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:100 - 1:200
Protein Name Anti-KLK11 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLK11 (NP_001129504.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 31.1 kDa
Database Links
Alternative Names KLK11Kallikrein-11 antibodyhK11KLK11 antibodyPRSS20 antibodyTLSP antibodyUNQ649/PRO1279
Function Possible multifunctional protease, Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin, Cleaves synthetic peptides after arginine but not lysine residues.
Cellular Localization Secreted
Tissue Specificity Expressed in brain, skin and prostate, isoform 1 is expressed preferentially in brain, isoform 2 is expressed in prostate, present in seminal plasma at concentrations ranging from 2 to 37 microg/ml (at protein level).
Swiss-Prot Key

 

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