Anti-KPTN Antibody

Rs. 61,689.00
SKU stj26692

General Information

Product name Anti-KPTN Antibody
Short Description Rabbit polyclonal to KPTN
Description This gene encodes a filamentous-actin-associated protein, which is involved in actin dynamics and plays an important role in neuromorphogenesis. Mutations in this gene result in recessive mental retardation-41. Alternatively spliced transcript variants have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-KPTN Antibody
Immunogen A synthetic Peptide of human KPTN
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.1 kDa
Database Links
Alternative Names KPTNKICSTOR complex protein kaptin antibodyActin-associated protein 2E4KPTN
Function As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway, Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases, Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids, In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated, The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.
Cellular Localization Lysosome membrane.
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF