Anti-KRT16 Antibody

Rs. 45,619.00
SKU stj29629

General Information

Product name Anti-KRT16 Antibody
Short Description Rabbit polyclonal to KRT16
Description The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-KRT16 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 190-430 of human KRT16 (NP_005548.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 51.3 kDa
Database Links
Alternative Names KRT16Keratin antibodytype I cytoskeletal 16 antibodyCytokeratin-16 antibodyCK-16 antibodyKeratin-16 antibodyK16KRT16 antibodyKRT16A
Function Epidermis-specific type I keratin that plays a key role in skin, Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.
Cellular Localization
Tissue Specificity Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis, also found in luminal cells of sweat and mammary gland ducts
Swiss-Prot Key

 

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