Anti-KRT7 Antibody

Rs. 45,619.00
SKU stj24364

General Information

Product name Anti-KRT7 Antibody
Short Description Rabbit polyclonal to KRT7
Description The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-KRT7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human KRT7 (NP_005547.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 51.4 kDa
Database Links
Alternative Names KRT7Keratin antibodytype II cytoskeletal 7 antibodyCytokeratin-7 antibodyCK-7 antibodyKeratin-7 antibodyK7 antibodySarcolectin antibodyType-II keratin Kb7KRT7 antibodySCL
Function Blocks interferon-dependent interphase and stimulates DNA synthesis in cells, Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Cellular Localization Cytoplasm
Tissue Specificity Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver, observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Swiss-Prot Key

 

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