Anti-KYNU Antibody

Rs. 45,619.00
SKU stj28726

General Information

Product name Anti-KYNU Antibody
Short Description Rabbit polyclonal to KYNU
Description Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-KYNU Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human KYNU (NP_001028170.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 52.4 kDa
Database Links
Alternative Names KYNUKynureninase KYNU
Function Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively, Has a preference for the L-3-hydroxy form, Also has cysteine-conjugate-beta-lyase activity.
Cellular Localization Cytoplasm, cytosol
Tissue Specificity Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas), highest levels found in placenta, liver and lung, expressed in all brain regions.
Swiss-Prot Key

 

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