Anti-Lamin B1 antibody

Rs. 50,211.00
SKU stj93887

General Information

Product name Anti-Lamin B1 antibody
Short Description Rabbit polyclonal to Lamin B1.
Description Lamin B1 is a protein encoded by the LMNB1 gene which is approximately 66,4 kDa. Lamin B1 is localised to the nuclear inner membrane. It is involved in the apoptosis and survival caspase cascade , mitotic cell cycle, granzyme pathway and CDK-mediated phosphorylatin. It is one of the two B-type lamin proteins and is a component of the nuclear lamina. It is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin B1 is expressed in the liver, nervous system, eye, heart and intestine. Mutations in the LMNB1 gene result in autosomal dominant, adult-onset leukodystrophy. stj93887 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Lamin B1 protein.
Applications WB,IHC,ELISA,IF
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-Lamin B1 antibody
Immunogen Synthesized peptide derived from human Lamin B1.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 67 kDa
Database Links
Alternative Names Lamin-B1 antibody
LMN2 antibody
LMNB antibody
Function Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Cellular Localization Nucleus inner membrane. Lipid-anchor. Nucleoplasmic side.
Tissue Specificity
Swiss-Prot Key

 

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