Anti-LARP7 Antibody

Rs. 61,689.00
SKU stj27779

General Information

Product name Anti-LARP7 Antibody
Short Description Rabbit polyclonal to LARP7
Description This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-LARP7 Antibody
Immunogen A synthetic peptide of human LARP7
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 66.9 kDa
Database Links
Alternative Names LARP7La-related protein 7 antibodyLa ribonucleoprotein domain family member 7 antibodyP-TEFb-interaction protein for 7SK stability antibodyPIP7SLARP7 antibodyHDCMA18P
Function Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system, Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Cellular Localization Nucleus, nucleoplasm
Tissue Specificity
Swiss-Prot Key

 

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