Anti-LBR Antibody

Rs. 45,619.00
SKU stj27421

General Information

Product name Anti-LBR Antibody
Short Description Rabbit polyclonal to LBR
Description The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-LBR Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR (NP_002287.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 70.7 kDa
Database Links
Alternative Names LBRLamin-B receptor antibodyIntegral nuclear envelope inner membrane protein antibodyLMN2RLBR
Function Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Cellular Localization Nucleus inner membrane
Tissue Specificity
Swiss-Prot Key

 

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