Anti-LIN7B Antibody

Rs. 68,577.00
SKU stj70478

General Information

Product name Anti-LIN7B Antibody
Short Description Goat polyclonal to LIN7B
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-LIN7B Antibody
Immunogen N Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 22.9 kDa
Database Links
Alternative Names LIN7BProtein lin-7 homolog B antibodyLin-7B antibodyhLin7B antibodyMammalian lin-seven protein 2 antibodyMALS-2 antibodyVertebrate lin-7 homolog 2 antibodyVeli-2 antibodyhVeli2LIN7B antibodyMALS2 antibodyVELI2 antibodyUNQ3116/PRO10200
Function Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells, Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains, The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain, Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin, Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells, May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity),
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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