Anti-LPCAT2 Antibody

Rs. 45,619.00
SKU stj26877

General Information

Product name Anti-LPCAT2 Antibody
Short Description Rabbit polyclonal to LPCAT2
Description This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-LPCAT2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 160-544 of human LPCAT2 (NP_060309.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 60.2 kDa
Database Links
Alternative Names LPCAT2Lysophosphatidylcholine acyltransferase 2 antibodyLPC acyltransferase 2 antibodyLPCAT-2 antibodyLysoPC acyltransferase 2LPCAT2 antibodyAGPAT11 antibodyAYTL1
Function Possesses both acyltransferase and acetyltransferase activities, Activity is calcium-dependent, Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF), Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor, Under resting conditions, acyltransferase activity is preferred, Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases, Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed