Anti-LRP1 antibody

Rs. 50,211.00
SKU stj93954

General Information

Product name Anti-LRP1 antibody
Short Description
Description Rabbit polyclonal to LRP1.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-LRP1 antibody
Immunogen Synthesized peptide derived from human LRP1 around the non-phosphorylation site of S4520.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 50 kDa
Database Links
Alternative Names Prolow-density lipoprotein receptor-related protein 1 antibody
LRP-1 antibody
Alpha-2-macroglobulin receptor antibody
A2MR antibody
Apolipoprotein E receptor antibody
APOER antibody
CD antigen CD91 antibody
Low-density lipoprotein receptor-related protein 1 85 kDa subunit antibody
LRP-85 antibody
Low-density lipoprotein receptor-related protein 1 515 kDa subunit antibody
LRP-515 antibody
Low-density lipoprotein receptor-related protein 1 intracellular domain antibody
LRPICD antibody
A2MR antibody
APR antibody
Function Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission . Acts as an alpha-2-macroglobulin receptor . (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Cellular Localization Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane. Single-pass type I membrane protein. Membrane, coated pit.. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane. Peripheral membrane protein. Extracellular side. Membrane, coated pit.. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm. Nucleus. After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus.
Tissue Specificity Most abundant in liver, brain and lung.
Swiss-Prot Key

 

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