Anti-LUCA15 antibody

Rs. 50,211.00
SKU stj93969

General Information

Product name Anti-LUCA15 antibody
Short Description
Description Rabbit polyclonal to LUCA15.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-LUCA15 antibody
Immunogen Synthesized peptide derived from human LUCA15
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 92 kDa
Database Links
Alternative Names LUCA15
RNA-binding protein 5 antibody
Protein G15 antibody
Putative tumor suppressor LUCA15 antibody
RNA-binding motif protein 5 antibody
Renal carcinoma antigen NY-REN-9 antibody
H37 antibody
LUCA15 antibody
Function Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Cellular Localization Nucleus
Tissue Specificity Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.
Swiss-Prot Key

 

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