Anti-LZTS1 Antibody

Rs. 61,689.00
SKU stj26256

General Information

Product name Anti-LZTS1 Antibody
Short Description Rabbit polyclonal to LZTS1
Description This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Anti-LZTS1 Antibody
Immunogen A synthetic peptide of human LZTS1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 66.6 kDa
Database Links
Alternative Names LZTS1Leucine zipper putative tumor suppressor 1 antibodyF37/esophageal cancer-related gene-coding leucine-zipper motif antibodyFez1LZTS1 antibodyFEZ1
Function Involved in the regulation of cell growth, May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation, May act as a tumor suppressor.
Cellular Localization Cytoplasm.
Tissue Specificity Highly expressed in testis, prostate, spleen, thymus, ovary and brain, detected at lower levels in heart, placenta, small intestine, colon, liver, kidney, skeletal muscle and pancreas, not detectable in primary tumors from breast and prostate and in many cancer cell lines.
Swiss-Prot Key

 

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